We're thrilled to announce that COSMIC-3D, our platform for exploring the protein sequence and structural nature of COSMIC cancer mutations, has just been published in Nature Genetics.
As part of release v86 we have focused on updating the expert-curated mutation data for glioblastoma multiforme (GBM). Approximately 70 additional publications that include mutation screening data in this disease are included in the release.
The August COSMIC release (v86) has just gone live! We have 3 newly curated genes: CHD4, IRS4 and CTCF; and the newly curated fusion pair MN1-ETV6. As part of this release we have also completed a body of curation focused on Glioblastoma.
In the near future, we are redeveloping our website and would love to hear how you interact with it, finding out what works well and what doesn’t. Sign up now to have your say!
We have introduced a new way of managing the COSMIC accounts by asking you to annually revalidate your account. In this post, we provide a step by step guide of how to do this and keep your account active.
The May COSMIC release (v85) is now live. There are 3 new fully curated genes, substantial curation updates for TERT, 1 new fusion pair, and 162 whole genome screened samples from 8 new systematic screen papers. We have also added 25 new genes to the Cancer Gene Census Hallmarks of Cancer and added a new track to the main Genome Browser which displays mutation recurrence.
The COSMIC SFTP server email@example.com will be deprecated in August 2018.
We have a new file download service to replace our SFTP server to provide a simpler and more reliable download service. Files can be downloaded via a standard HTTPS request from any client to `cancer.sanger.ac.uk/cosmic/file_download`.
Research takes time, so it's not always possible to be making use of the latest version of COSMIC. As we've changed how programmatic file downloads work for the current release, there is also a new method for accessing archived releases.
To celebrate International Women’s Day 2018, our Staff Scientist, Sam who has been working with COSMIC since 2016, has written a short bio of her journey working in science.