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NEW: The Cancer Mutation Census!

1 Jul 2020

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About the product

The Cancer Mutation Census (CMC) is an undertaking to classify coding mutations in COSMIC and identify variants driving different types of cancer. The CMC integrates all coding somatic mutations collected by COSMIC with biological and biochemical information from multiple sources, combining data obtained from manual curation and computational analyses. Metrics like ClinVar significance, dN/dS ratios, and variant frequencies in normal populations (gnomAD) have been integrated into this resource. They have been used alongside COSMIC data on mutations' prevalence across 1,500 forms of human cancer. This helps to predict candidates for driver mutations in the coding portion of the genome.

A brand new look website

Users will also be able to explore and visualise the data in a new website.

Please note the following designs may be different from the released product and are used to illustrate some of the content available in The Cancer Mutation Census website.

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We'd love to hear from you!

We really value your opinion and would like to share an early preview of the CMC beta website with you and any interested colleagues, in exchange for any feedback you may have to offer. If you would like to help shape the future of COSMIC please email us at cosmicengagement@sanger.ac.uk.

About

COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the most comprehensive resource for exploring the impact of somatic mutations in human cancer. Here on our news page we aim to give you an insight into what we are doing and why. We will keep you updated with new developments and release information as well as any events we are hosting.